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Raw Material Powder 99% Injectable Peptides Bodybuilding PEG MGF Mechano Growth Factor Powder Pharmarceutical Grade

Categories Pharmaceutical Peptides
Brand Name: Mechano Growth Factor
Model Number: powder
Certification: GMP
Place of Origin: China
MOQ: 100vials
Price: negotiation
Payment Terms: Western Union,Money Gram or T/T
Supply Ability: 10000vials per month
Delivery Time: 3-5days
Packaging Details: carton box
Delivery time: 3-5days
Certificate: GMP
Grade Standard: Medicine Grade, Tech Grade
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Raw Material Powder 99% Injectable Peptides Bodybuilding PEG MGF Mechano Growth Factor Powder Pharmarceutical Grade


Product Description:
Mechano Growth Factor (MGF) also known as IGF-1Ec is a grow factor/repair factor that is derived from exercised or damaged muscle tissue, Its called MGF as IGF-1Ec is a bit of a mouthful and harder to identify amongst the other igf variants.What makes MGF special is its unique role in muscle growth. MGF has the ability to cause wasted tissue to grow and improve itself by activating muscle stem cells and increasing the upregulation of protein synthesis, this unique ability can rapidly improve recovery and speed up muscle growth.
MGF (mechano growth factor) has been used by bodybuilders and athletes for a few years already. After resistance exercise,IGF-1 is released within the muscle. Specifically, at this time, immediately following the mechanical use of a muscle, the IGF-I gene is spliced towards MGF which initiates hypertrophy and repair of local muscle damage. It does so both by activating muscle stem cells and satellite cells, but also via various other anabolic processes. It differs from "regular" IGF-1 mainly due to it's C-Terminal sequence.
MGF Peptide is a much commonly used abbreviation for "Mechano Grow Factor" peptide which is a very popular exercise supplement used by body builders & athletes. The biomolecule was first discovered & documented by a well known biochemist called Goldspink. It is also known as "I-G-F-1EC"and is derived from damaged or worn out tissue. The peptide molecule is known to initiate repair of damaged tissues or local muscles and is released into the body after extensive training, resistance exercise etc. However, one should note that the peptide is chemically different from commonly found "I-GF-1" due to the existence of a C Terminal Sequence.
Quick Detail :
PEG-MGF
Alias: PEG-Suc-YQPPSTNKNTKSQ(d)R(d)RKGSTFEEHK-NH2; PEG-Suc-Tyr-Gln-PRO-PRO-Ser-Thr-Asn-Thr-Lys-Ser-Gln-D-Arg-Lys-Gly-Ser-Thr-Phe-Glu-Glu-His-Lys-NH2
M.F.: C121H200N42O39
Purity (HPLC): 97.0%
Packing: 2mg/vial,10vials/kit
Appearance: White powder
Storage :Lyophilized Peg MGF is stable at room temperature for 90 days,however it should be stored
in a freezer below -8C for any extended period of time. After reconstituting Peg MGF should be
refrigerated at temperatures not to exceed 36 F.
Usage: Peptides for use of pharmaceutical intermediates .
COA :
AppearanceWhite to off white powderConsistent
Purity(HPLC)≥95%97.30%
Water<6.0%5.60%
Acetic Acid3.0-8.0%6.45%
Trifluoroacetic Acid<0.25%0.12%
Peptide≥80%83.45%
MSConsistentConsistent
Product Application:
It was first discovered in the muscle by Goldspink, et al. In human muscle, a 49-base insert changes the reading frame in mechano grow factor (MGF) as compared to IGF-1.When mechanical overload is introduced to a muscle (as by weight training), the IGF-1 gene released and is differentially spliced during the bodies response. Initially, it it is spliced to produce predominantly IGF-1Ec (called the MGF splice variant of IGF-1). This early splicing stimulates satellite cells into activation. Which in turn allows the activation of extra undamaged nuclei to grow new muscle fiber and tissue.
The appearance of MGF also initiates the upregulation of new protein synthesis. After this initial splicing of IGF-1 into MGF, production then switches towards producing a systemic release of IGF-1Ea from the liver, which also upregulates protein synthesis as well. The expression of IGF-1 splice variants, over the course of the healing and regrowth phase of muscle repair is thought to be the primary anabolic mechanism by which the body produces new muscle. MGF is available as an injectable peptide, and it has been anecdotally shown that injecting it will cause a response in the area resulting in localized muscle growth.
MGF (mechano growth factor) has been used by bodybuilders and athletes for a few years already. After resistance exercise,IGF-1 is released within the muscle. Specifically, at this time, immediately following the mechanical use of a muscle, the IGF-I gene is spliced towards MGF which initiates hypertrophy and repair of local muscle damage. It does so both by activating muscle stem cells and satellite cells, but also via various other anabolic processes. It differs from "regular" IGF-1 mainly due to it's C-Terminal sequence. MGF can initiate muscle satellite (stem) cell activation in addition to its IGF-Ireceptor domain which ithen in turn increases protein synthesis turnover, and therefore can if used correctly improve muscle mass over time.
HOW TO USE MGF
When you train, what happens to your muscles is they break down, the cells are damaged, muscle tissue needs to be repaired and your body produces 2 forms of MGF splice variant. The first initial release of the above mentioned number 1 variant from the liver helps muscle cell recovery, if there is no MGF then muscle cells die.
As muscle is a post-mitotic tissue and as such cell replacement is not a means of tissue repair, if the cells are not repaired they die and your muscles get smaller and weaker. In muscle tissue, the pool of these stem cells is apparently replenished by the action of MGF, which is produced as a pulse following damage.
Now, with synthetic injections of MGF you can increase the pulse and so speed up recovery, and increase the muscle tissue cells by stimulating satellite cells into full maturity. In terms of dosages, 200mcg bi-laterally is the very best choice of dosing in muscles trained.
The only problem with MGF, and this is the reason I don't like it, is that it has such a short half life, just a few minutes, between 5-7, and it needs to be used immediately post workout as it wont work if muscle tissue hasn’t been damaged. That's why, for me personally, I think the best option is PEG MGF.
Nevertheless, MGF has a huge role to play, and is administered to those with muscle wasting diseases and for those who are elderly and have lost muscle mass for good reason, it is EXTREMELY anabolic.
MGF Dosage
A typical protocol would be:
100-300mcg of MGF divided into 1-2 bilateral administrations in 2-5 different areas of the muscles approximately 5-7 days a week - intramuscular injections.
Example, if you want to administer 200mcg of MGF into the chest and biceps muscles 2 times a day and 3 different areas of the muscle then you would need to divided the dose as follows:
200mcg / 2 times per day = 100mcg per administration
100mcg per administration / 4 muscles (2 chest and 2 bicep muscles) = 25mcg per muscle
25mcg per muscle / 3 different locations on each muscle = 8.3mcg per injection
Theoreticall, the more locations used to administer the MGF into the muscle the more places for muscle growth.
Quality Raw Material Powder 99% Injectable Peptides Bodybuilding PEG MGF Mechano Growth Factor Powder Pharmarceutical Grade for sale
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