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Theophylline Pharmaceutical Raw Materials Methylxanthine For COPD Treatment CAS 58-55-9

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Brand Name: Pharmasupply
Model Number: Methylxanthine Powder
Certification: ISO9001, USP, BP, GMP
Place of Origin: Hubei, China
MOQ: 10g
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Name: Theophylline
Appearance: Powder
Assay: 99% min.
MOQ: 10g
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Theophylline Pharmaceutical Raw Materials Methylxanthine For COPD Treatment CAS 58-55-9

Theophylline Raw Powder Methylxanthine Used In The Treatment Of COPD CAS 58-55-9




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What is theophylline?


Theophylline is a "methylxanthine." This is a chemical that relaxes smooth muscle around the airways of the lungs. It also may act in other ways to help open the airways. There are other methylxanthines such as caffeine and theobromine. They are found in coffee, tea, and chocolate/cocoa, but they are not as strong as theophylline.


Theophyline For COPD

Theophyline is a bronchodilator that's been used in the treatment of COPD for more than seven decades. It is used to treat wheezing or shortness of breath caused by asthma, bronchitis, emphysema and other breathing disorders. It works by relaxing the muscles in the lungs and chest, making it easier to breathe.
How does theophylline for COPD work?
Theophyline is part of the methylxanthines class. It has two different mechanisms of action in people with reversible lung obstruction: as a bronchodilator, it causes smooth muscle relaxation. Its non-bronchodilator effects suppress the response of the airways to stimuli.
Its mechanism of action is not fully known, although animal studies suggest that the bronchodilation involves the inhibition of two phosphodiesteraseenzymes(PDE ll and PDE IV) while the suppressive effects are probably due to different mechanisms that do not involve these enzymes.


Theophylline also increases the force of contraction of diaphragmatic muscles, probably due to the increase of intracellular calcium through an adenosine-mediated channel. It hasn't been used as often as it was in the past as better-tolerated and more effective bronchodilators have come on the market.


Studies of theophylline

Studies of people with COPD have shown that theophylline decreases dyspnea, air trapping, and breathing difficulties, and increases diaphragmatic muscle contraction force.


What are possible theophylline side effects?
The side effects include:

  • headache
  • irritability
  • nervousness
  • fast, pounding, or irregular heart beat
  • restlessness
  • insomnia
  • tremors
  • light-headedness
  • seizures
  • nausea
  • stomach ache
  • diarrhea
  • loss of appetite

If I have side effects early on, when can I expect side effects to disappear?
Many people do not have side effects. If you have side effects early on, they often disappear after the first week of treatment. If side effects persist, or if they make you uncomfortable, notify your doctor. Other medicines and illnesses also cause these symptoms. If you experience side effects at the start of therapy, the first four days can be the worst, with side effects improving after that.



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Product Name:Theophylline
Synonyms:High purity Theophylline CAS NO.58-55-9;Caffeine Impurity 1(Caffeine EP Impurity A);Theophylline Anhydrous powder;1,3-Dimethyl-3,7-dihydro-1H-purine-2,6-dione;1,3-dimethyl-xanthin;Pentoxifylline Impurity 3(Pentoxifylline EP Impurity C);1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-;3,7-dihydro-1,3-dimethyl-1h-purine-6-dione

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