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High Purity Pharmaceutical Intermediate Peptide Glucagon (1-29) ( Human ) CAS 16941-32-5

Categories Polypeptide Hormones
Brand Name: HKYC
Model Number: 16941-32-5
Certification: KOSHER/ISO9001/SGS
Place of Origin: China
MOQ: 10g
Price: 1USD
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 500kg/month
Delivery Time: 3-7 days
Packaging Details: Discreet package or as required.
Shipment: EMS, TNT, DHL, China Post
Appearance: White Powder
Color: white
Payment: T/T,Western Union, Moneygram,Bitcoin
Email: Fredeboo@chembj.com
Skype: live:fredeboo_2
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High Purity Pharmaceutical Intermediate Peptide Glucagon (1-29) ( Human ) CAS 16941-32-5


High Purity Pharmaceutical Intermediate Peptide Glucagon (1-29) ( Human ) CAS 16941-32-5


Basic Info.


Glucagon(1-29)(Human)
Sequence:H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH
Alias:Glucagon(pig),Bovineglucagon,Glucagon(Canisfamiliaris stomach),Glucagon(Mesocricetus auratus),Glucagon(Saimirisciureus),Glucagon(Xenopus aevis),Glucagon (dog pancreas),Glucagon (dog),Glucagon (human),Glucagon (ox), Glukagon Novo, Human glucagon
Cas No. : 16941-32-5
Molecular Formula : C153H225N43O49S
Molecular Weight: 3482.75
Purity (HPLC) : 99.0%min.
Appearance: White powder

Usage : Glucagon is a promoting hormone catabolism, glucagon has very strong promoting glycogenolysis and gluconeogenesis, make blood sugar rise significantly, activation of liver cells phosphorylase, acceleration of glycogenolysis, glucagon can also activate lipases, promote fat decomposition, and can enhance fat acid oxidation, so that ketogenesis increase, in addition, the secretion of glucagon may promote insulin and islet somatostatin.


Description:

Glucagon is also known as glucagon or anti insulin or insulin B. It is accompanied by a hormone insulin secretion from pancreatic islet alpha cells of vertebrates. Confrontation and insulin plays a role, increase blood glucose. In 1953, was isolated by precipitation and obtain the crystallization. It is based on the N- terminal histidine as a starting point, C terminal threonine is a single chain peptide terminus of 29 amino acids (molecular weight is about 3500), does not have the S-S bonds in a molecule, at this point, completely different from insulin. The structure of the compound has been synthesized by chemical recent affirmation. The early effect of glucagon process is specific binding exists in the target cell receptors on the cell membrane, the adenylate cyclase activation, ring type AMP as the second messenger activating phosphorylase, promoting glycogenolysis.


Application:

In contrast to the action of insulin, glucagon is a promoting hormone catabolism. Glucagon has very strong promoting glycogenolysis and gluconeogenesis, make the blood glucose increased significantly, 1mol/L hormone can make 3 x 106mol/L glucose from glycogen decomposed rapidly out. Glucagon by cAMP-PK system, the activation of hepatic cells accelerated glycogen phosphorylase, decomposition. Gluconeogenesis is enhanced because hormone accelerate amino acids into liver cells, and activate the enzyme of gluconeogenesis.
Glucagon also activates lipase, promote fat decomposition, and can enhance the oxidation of fatty acid, so that increased ketogenesis. The target organ of glucagon produced the metabolic effects of the liver, liver resection or interruption of hepatic blood flow, these effects disappeared.
In addition, the secretion of glucagon may promote insulin and islet somatostatin. Pharmacological doses of glucagon can make the content of cAMp in myocardial cells increased, myocardial contraction enhancement.


COA


Product nameGlucagon(1-29)(Human)
Cas No.16941-32-5
Molecular FormulaC153H225N43O49S
Molecular Weight3482.82
Purity (HPLC)99.0%min
AppearanceWhite powder
Single Impurity(HPLC)0.5%max
Amino Acid Composition±10% of theoretical
Peptide Content(N%)≥75.0%
Water Content(Karl Fischer)≤8.0%
HCl Content (HPIC)≤10.0%
Specific Rotation (20/D)-37.0~-47.0°(c=1 1%HAc)
MS(ESI)Consistent
Mass Balance95.0~105.0%


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Payment

T/T , Western Union, Money Gram, Bitcoins.


Our Advantages:


1.Rich experience.We are a professional trading company in China for many years,our products have exported to Germany,Spain,UK,USA,Australia,Middle East and so many other countries,and we have got very good feedback from our customers,we had Established many long friendly relations of cooperation.
2.Great quality,purity and competitive price.
3.Safe and fast delivery.
4.Good after-sales service.

Tracking number:

EMS:

EA276218706HK

EA276076852HK

EA272838620HK

DHL:

8124222794

1667845944

6338036386


Email:Fredeboo@chembj.com

Skype:live:fredeboo_2

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