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99.05% High Purity Pharmaceutical Intermediate Misoprostol White Solid

Categories Pharmaceutical Raw Materials
Brand Name: TINGYI
Model Number: CAS: 59122-46-2
Certification: GMP , ISO 9001:2008
Place of Origin: CHINA
MOQ: 10g
Price: Contact Us
Payment Terms: Bank Transfer - Bitcoin - Western Union - MoneyGram
Supply Ability: 300 KG/Month
Delivery Time: Within 7 Working Days
Packaging Details: Stealth And Discreet Packaging
Product Name: Misoprostol
Other Name: CYTOTEC
MF: C22H38O5
MW: 382.54
MP: 261-263°C
Storage temp: 20°C
Appearance: White Solid
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99.05% High Purity Pharmaceutical Intermediate Misoprostol White Solid


99.05% High Purity Pharmaceutical Intermediate Misoprostol White Solid


Description:

Misoprostol is a medication used to start labor, induce abortions, prevent and treat stomach


ulcers, and treat postpartum bleeding due to insufficient contraction of the uterus. For abortions it


is used with mifepristone or methotrexate. It is a synthetic prostaglandin E1 (PGE1).


Common side effects include diarrhea and abdominal pain. It is pregnancy category X meaning


that it is known to result in negative fetal outcomes if taken during pregnancy. Uterine rupture may


occur.


Usage:

Misoprostol acts upon gastric parietal cells, inhibiting the secretion of gastric acid by G-protein


coupled receptor-mediated inhibition of adenylate cyclase, which leads to decreased intracellular


cyclic AMP levels and decreased proton pump activity at the apical surface of the parietal cell.


Because other classes of drugs, especially H2-receptor antagonists and proton pump inhibitors,


are more effective for the treatment of acute peptic ulcers, misoprostol is only indicated for use by


people who are both taking NSAIDs and are at high risk for NSAID-induced ulcers, including the


elderly and people with ulcer complications. Misoprostol is sometimes coprescribed with


NSAIDs to prevent their common adverse effect of gastric ulceration.


Misoprostol has other protective actions, but is only clinically effective at doses high enough to


reduce gastric acid secretion. For instance, at lower doses, misoprostol may stimulate increased


secretion of the protective mucus that lines the gastrointestinal tract and increase mucosal blood


flow, thereby increasing mucosal integrity. However, these effects are not pronounced enough to


warrant prescription of misoprostol at doses lower than those needed to achieve gastric acid


suppression.


However, even in the treatment of NSAID-induced ulcers, omeprazole proved to be at least as


effective as misoprostol,but was significantly better tolerated, so misoprostol should not be


considered a first-line treatment. Misoprostol-induced diarrhea and the need for multiple daily


doses are the main issues impairing compliance with therapy.




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Quality 99.05% High Purity Pharmaceutical Intermediate Misoprostol White Solid for sale
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