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CAS 162401-32-3 pharma raw materials Respiratory System Drugs Roflumilast for COPD

Categories Pharmaceutical Raw Materials
Brand Name: Kafen
Model Number: 162401-32-3
Certification: GMP,ISO,UKAS
Place of Origin: China
MOQ: 10g
Price: Negotiable
Payment Terms: T/T, Western Union, MoneyGram,Bitcoin
Supply Ability: 5000KG/Month
Delivery Time: Within 24 hours after receiving your payment
Packaging Details: As your request
CAS: 162401-32-3
Purity: 99%
MF: C17H14Cl2F2N2O3
MW: 403.21
MP: 158°C
Appearance: Crystallin Solid
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CAS 162401-32-3 pharma raw materials Respiratory System Drugs Roflumilast for COPD


Pharmaceutical Raw Materials Respiratory System Drugs Roflumilast for COPD CAS:162401-32-3


Basic Info.

Roflumilast
Synonyms: ROFLUMILAST;3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide;B 9302-107;BY 217;BYK 20869;Daxas;Roflumilast / 3-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide;3-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide
CAS: 162401-32-3
MF: C17H14Cl2F2N2O3
MW: 403.21
MP: 158°C
storage temp. Refrigerator
Chemical Properties Crystallin Solid
Usage Selective phosphodiesterase 4(PDE4) inhibitor. Antiasthmatic; in treatment of chronic obstructive pulmonary disease
Purity: 99%
Usage: API
Package: 1KG foil bag; 25Kg drum


Description:


Roflumilast is a phosphodiesterase-4 (PDE-4) inhibitor. Due to its selective inhibition of the PDE4 isoenzyme in lung cells, roflumilast is indicated for the management of chronic obstrtuctive pulmonary disease (COPD) exacerbations. Treatment with Roflumilast is associated with an increase in psychiatric adverse reactions, including suicide and suicidal attempts.


COA:


TestsSpecificationsResults
CharactersWhite to off-white crystalline powderComplies
IdentificationIR:similar to Reference StandardComplies
Appearance of solutionClear and colorlessComplies
Loss on Drying≤0.5%0.06%
Sulphated Ash≤0.2%0.03%
Heavy metals≤0.002%Complies
Related Compouds
  1. Single Impurity ≤1.0%
  2. Sum of Impurity≤2.0%

Undetected

Undetected

Assay(Anhydrous)98.0% to 101.5%100.2%

Function:


Roflumilast can be used for the prevention and treatment of respiratory disease, and used for the treatment of severe chronic obstructive pulmonary disease (COPD) and excessive mucus cough bronchitis, asthmatic bronchitis, bronchial asthma, respiratory tract associated with abnormal secretion of acute and chronic bronchitis, air sacculitis, etc.


Chronic obstructive pulmonary disease (referred to as "COPD"), is chronic lung disease that characterized by incompletely reversible airflow obstruction. It is usually manifested clinically recurrent cough, sputum, dyspnea and other symptoms. That usually shows progressive progress features, including the vast majority of chronic bronchitis and emphysema. As the disease progresses, it will lead to airway remodeling, and ultimately develop to irreversible airflow obstruction, or coexist with asthma overlap. Therefore, improving the control of airflow obstruction and inflammation is the main goal of drug research at home and abroad.


Chronic obstructive pulmonary disease (COPD) is one of progressive and life-threatening lung disease and one of the human health "killer". It makes dyspnea, loss of activity. The disease typically includes chronic bronchitis and emphysema. It is estimated that about 210 million people worldwide suffer from the disease, and COPD will become the third largest cause of death in the world by 2020. Based on the conclusions of the US National Heart, Lung, and Blood Institute, smoking is the major risk factor for COPD.


Delivery and Packaging :

We have professional team for package and shipment. Special way to ship 100 grams to 100kg powders at one time to your country. Fast and discreet shipment could be arranged for customs pass Guaranteed.


Competitive Advantage:

1. Rich experience.
Having been specialized in this field for years, we have rich experience and widespread sales network around the word. Our steroid and hormones have been exported to overseas, like Europe, Africa, Asia, America and other countries. We are not got good feedback from our guest, but also established long business relationship with them.

2. Great quality and high purity.
Good quality is one secret for our success. All of our products enjoys high purity. Thus, it can make sure our client's need. Welcome order the samples, MOQ just 10 grams.

3. Safest and fastest delivery.
We have mass stock, so that we can arrange the delivery within 24hours once receiving the payment. Tracking number would be informed quickly after shipment. We have our own way of packing which could ship 0.01 kilo to 50 kilo products a time.

4. Good after-sales service.
24/7 is available. We will tell you the package updated info ASAP. And try our best to solve various problems customers encountered!

5. Experiential shopping.
Besides raw steroid powder and liquid, we offer hormone solution and formula. We can teach you how to make hormone solution on the site. Any visit to our lab is welcomed.


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